Indications and Usage
PANHEMATIN (hemin for injection) is a prescription medication used to relieve repeated attacks of acute intermittent porphyria related to the menstrual cycle in affected women.
Signs and symptoms of acute intermittent porphyria such as pain, high blood pressure, rapid heart beat, abnormal mental status and mild to progressive neurologic signs (including seizures and paralysis) may be controlled in some patients with this disorder.
Similar findings have been reported in other patients with acute intermittent porphyria, porphyria variegata and hereditary coproporphyria. PANHEMATIN is not indicated in porphyria cutanea tarda.
PANHEMATIN does not cure acute intermittent porphyria. After stopping PANHEMATIN treatment, symptoms usually return, although some patients experience a period without symptoms.
To learn more about Panhematin, please visit www.AIPorphyria.com.
Important Safety Information
| PANHEMATIN should only be used by physicians experienced in the management of porphyrias in hospitals where the recommended clinical and laboratory diagnostic and monitoring techniques are available. PANHEMATIN therapy should be considered after an appropriate period of alternate therapy (i.e., 400 g glucose/day for 1 to 2 days). |
PANHEMATIN is not for patients known to be allergic to this drug. PANHEMATIN is made from human blood and therefore may contain agents that can cause infections, such as viruses, that can cause disease including Creutzfeldt-Jakob disease.
Drugs such as estrogens, barbituric acid derivatives, steroid-like drugs, and blood thinners should be avoided during PANHEMATIN therapy. Your doctor should monitor your iron levels if you receive multiple courses of PANHEMATIN.
Reversible kidney shutdown has occurred with high doses. Because vein inflammation has been reported after administering PANHEMATIN through small arm veins, a large arm vein or a central line should be used.
For more information, please see Full Prescribing Information including Boxed Warning.
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