Publication title Author Source Drug Year
Involvement of 5-HT7 receptors in vortioxetine’s modulation of circadian rhythms and episodic memory in rodents Westrich L, Haddjeri N, Dkhissi-Benyahya O, Sanchez C Neuropharmacology 2015;89:382-390 Vortioxetine 2015 View abstract
Treatment of cognitive dysfunction in major depressive disorder - a review of the preclinical evidence for efficacy of selective serotonin reuptake inhibitors, serotonin-norepinephrine reuptake inhibitors and the multimodal-acting antidepressant vortioxetine Pehrson AL, Leiser SC, Gulinello M, Dale E, Li Y, Waller JA, Sanchez C European Journal of Pharmacology 2015;753:19-31 Citalopram; Escitalopram; Vortioxetine 2015 View abstract
Patient-Centered Outcomes With Aripiprazole Once-Monthly for Maintenance Treatment in Patients With Schizophrenia Kane JM, Sanchez R, Baker RA, Eramo A, Peters-Strickland T, Perry PP, Johnson BR, Tsai LF, Carson WH, McQuade RD, Wolfgang Fleischhacker W. Clinical schizophrenia and related psychoses 2015; E-pubulished Feb 24, 2015 - 2015 View abstract
Altered y-aminobutyric acid neurotransmission in major depressive disorder: a critical review of the supporting evidence and the influence of serotonergic antidepressants Pehrson AL, Sanchez C Drug Design, Development and Therapy 2015;9:603-624 Vortioxetine 2015 View abstract
The antipsychotic-like effects in rodents of the positive allosteric modulator Lu AF21934 involve 5-HT<sub>1A</sub> receptor signaling: mechanistic studies Wieronska JM, Slawin´ska A, Lason´-Tyburkiewicz M, Gruca P, Papp M, Zorn SH, Doller D, Kleczek N, Noworyta-Sokolowska K, Golembiowska K, Pilc A Psychopharmacology 2015;232(1):259-273 - 2015 View abstract
The solid-state continuum: A perspective on the interrelationships between different solid-state forms in drug substance and drug product Elder DP, Patterson JE, Holm R Journal of Pharmacy and Pharmacology 2015;67(6):757-772 - 2015 View abstract
Neonatal Levels of Inflammatory Markers and Later Risk of Schizophrenia Nielsen PR, Agerbo E, Skogstrand K, Hougaard DM, Meyer U, Mortensen PB Biological psychiatry 2015;77(6):548-555 - 2015
Evaluation of Drug-Polymer Solubility Curves Through Formal Statistical Analysis: Comparison of Preparation Techniques Knopp MM, Olesen NE, Holm P, Lobmann K, Holm R, Langguth P, Rades T Journal of pharmaceutical sciences 2015;104(1):44-51 - 2015
Randomized Withdrawal Study of Patients With Symptomatic Neurogenic Orthostatic Hypotension Responsive to Droxidopa Biaggioni I, Freeman R, Mathias CJ, Low P, Hewitt LA, Kaufmann H, Droxidopa 302 Investigators Hypertension 2015;65(1):101-107 - 2015
In vivo and In vitro Evaluations of Intestinal Gabapentin Absorption: Effect of Dose and Inhibitors on Carrier-Mediated Transport Larsen MS, Frolund S, Nøhr MK, Nielsen CU, Garmer M, Kreilgaard M, Holm R Pharmaceutical research 2015;32(3):898-909 - 2015
Identification of specific mRNA signatures as fingerprints for carcinogenesis in mice induced by genotoxic and non-genotoxic hepatocarcinogens Kossler N, Matheis KA, Ostenfeldt N, Toft DB, Dhalluin S, Deschl U, Kalkuhl A Toxicological sciences 2015;143(2):277-295 - 2015
Hospitalization rates in patients switched from oral anti-psychotics to aripiprazole once-monthly: final efficacy analysis Kane JM, Zhao C, Johnson BR, Baker RA, Eramo A, McQuade RD, Duca AR, Sanchez R, Peters-Strickland T Journal of medical economics 2015;18(2):145-154 Aripiprazole 2015 View abstract
Management of depressive symptoms in schizophrenia: A pooled, post-hoc analysis from the asenapine development program Castle DJ, Jensen JKS Clinical schizophrenia and related psychoses 2015;9(1):13-20 Asenapine 2015 View abstract
In vivo toxicity of cationic micelles and liposomes Knudsen KB, Northeved H, Kumar Ek P, Permin A, Gjetting T, Andresen TL, Larsen S, Wegener KM, Lykkesfeldt J, Jantzen K, Loft S, Moller P, Roursgaard M Nanomedicine : nanotechnology, biology, and medicine 2015;11(2):467-477 - 2015 View abstract
Vortioxetine, a novel antidepressant with multimodal activity: Review of preclinical and clinical data Sanchez C, Asin KE, Artigas F Pharmacology and Therapeutics 2015;145:43-47 Citalopram; Escitalopram; Vortioxetine 2015 View abstract
The effects of taurine on Vigabatrin, high light intensity and mydriasis induced retinal toxicity in the pigmented rat Rasmussen AD, Truchot N, Pickersgill N, Thale ZI, Rosolen SG, Botteron C Experimental and Toxicologic Pathology 2015;67(1):13-20 Vigabatrin 2015 View abstract
Lasting treatment effects in a postmarketing surveillance study of prolonged-release melatonin Hajak G, Lemme K, Zisapel N International clinical psychopharmacology 2015;30(1):36-42 Circadin 2015
Pharmacotherapeutic strategies for patients treated for depression in UK primary care: a database analysis Lamy F, Chollet J, Clay E, Brignone M, Rive B, Saragoussi D Current medical research and opinion 2015;31(4):795-807 - 2015 View abstract
Emerging mechanisms and treatments for depression beyond SSRIs and SNRIs Dale E, Bang-Andersen B, Sanchez C Biochemical pharmacology 2015;95(2):81-97 - 2015 View abstract
Synthesis and SAR studies of analogues of 4-(3,3-dimethyl-butyrylamino)-3,5-difluoro-N-thiazol-2-yl-benzamide (Lu AA41063) as adenosine A<sub>2A</sub> receptor ligands with improved aqueous solubility Mikkelsen GK, Langgård M, Schrøder TJ, Kreilgaard M, Jørgensen EB, Brandt G, Griffon Y, Boffey R, Bang-Andersen B Bioorganic and Medicinal Chemistry Letters 2015;25(6):1212-1216 - 2015 View abstract
A 5-HT<sub>3</sub> receptor antagonist potentiates the behavioral, neurochemical and electrophysiological actions of an SSRI antidepressant Betry S, Overstreet S, Haddjeri S, Pehrson S, Bundgaard S, Sanchez S, Mork S Pharmacology Biochemistry and Behavior 2015;131:136-142 - 2015 View abstract
Urea and thiourea modified polypropyleneimine dendrimers clear intracellular a-synuclein aggregates in a human cell line Laumann K, Boas U, Larsen HM, Heegaard PMH, Bergström A Biomacromolecules 2015;16(1):116-124 - 2015 View abstract
Smart Program Design Through a Common Information Model Vasko L, Sundgren M, Bachmann P, Balinski K, Bleich N, Blom T, Eriksson H, Ferendo R, Forsberg K, King D, Mordiva A, Proeve J, Thomas L, Witch E, Simán M Therapeutic Innovation and Regulatory Science 2015;49(1):116-125 - 2015 View abstract
Synergistic antiarrhythmic effect of combining inhibition of Ca2+ -activated K+ (SK) channels and voltage-gated Na<sup>+</sup> channels in an isolated heart model of atrial fibrillation Kirchhoff JE, Goldin Diness J, Sheykhzade M, Grunnet M, Jespersen T Heart Rhythm 2015;12(2):409-418 - 2015 View abstract
Investigating the long-term effect of subchronic phencyclidine-treatment on novel object recognition and the association between the gut microbiota and behavior in the animal model of schizophrenia Physiology and Behavior 2015;141:32-39 - 2015 View abstract
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