Publications

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The following research papers and other scientific publications were co-authored by members of the Lundbeck staff from 2000 to date.

For more information, please access the Lundbeck Clinical Trial Registry.

Publication title Author Source Drug Year
New challenges in clinical research in paediatric psychopharmacology Auby P Neuropsychiatrie de l'Enfance et de l'Adolescence 2012;60(1):62-68 - 2012
Bifeprunox: a partial agonist at dopamine D(2) and serotonin(1A) receptors, influences nicotine-seeking behaviour in response to drug-associated stimuli in rats. Di Clemente A, Franchi C, Orru A, Arnt J, Cervo L Addiction biology 2012;17(2):274-286 Bifeprunox 2012 View abstract
Synthesis of N-alkylated amino acids using fluorous-tagged hydroxylamines Nielsen SD, Smith GP, Begtrupa M, Kristensen JL Tetrahedron 2012;67(29):5261-5267 - 2012 View abstract
Cost-effectiveness of memantine in moderate and severe Alzheimer's disease in Norway Rive B, Aarsland D, Grishchenko M, Cochran J, Lamure M, Toumi M International journal of geriatric psychiatry 2012;27(6):573-582 Memantine 2012 View abstract
The Oxygen-Mediated Synthesis of 1,3-Butadiynes in Continuous Flow: Using Teflon AF-2400 to Effect Gas/Liquid Contact Petersen Trine P, Polyzos Anastasios, O Brien Matthew, Ulven Trond, Baxendale Ian R, Ley Steven V ChemSusChem 2012;5(2):274-277 - 2012 View abstract
Consideration of allosterism and interacting proteins in the physiological functions of the serotonin transporter Zhong H, Sanchez C, Caron MG Biochemical Pharmacology 2012;83(4):435-442 Escitalopram 2012 View abstract
Randomized, phase III study results of clobazam in Lennox-Gastaut syndrome Ng YT, Conry JA, Drummond R, Stolle J, Weinberg MA Neurology 2012;77(15):1473-1481 + <A href="http://dx.doi.org/10.1212/WNL.0b013e318232de76" target= "new">Data Supplement</a> - 2012 View abstract
Occupancy of the Serotonin Transporter after Administration of Lu AA21004 and its Relation to Plasma Concentration in Healthy Subjects Areberg J, Luntang-Jensen M, Sogaard B, Nilausen DO Basic and clinical pharmacology and toxicology 2012;110(4):401-404 Vortioxetine 2012
The novel adenosine A2Aantagonist Lu AA47070 reverses the motor and motivational effects produced by dopamine D2 receptor blockade Collins LE, Sager TN, Sams AG, Pennarola A, Port RG, Shahriari M, Salamone JD Pharmacology Biochemistry and Behavior 2012;100:498-505 - 2012 View abstract
Severe and anxious depression: Combining definitions of clinical sub- types to identify patients differentially responsive to selective serotonin reuptake inhibitors Papakostas GI, Fan H, Tedeschini E European neuropsychopharmacology 2012;22(5):347-355 Escitalopram 2012 View abstract
Species Comparison of In Vivo P-glycoprotein Mediated Brain Efflux Using mdr1a Deficient Rats and Mice Bundgaard C, Jensen CJN, Garmer M Drug metabolism and disposition 2012;40(3):461-466 Citalopram 2012 View abstract
Pharmacological effects of Lu AA21004: a novel multimodal compound for the treatment of major depressive disorder Mork A, Pehrson A, Brennum LT, Moller NS, Zhong H, Lassen AB, Miller S, Westrich L, Boyle NJ, Sanchez C, Fischer CW, Liebenberg N, Wegener G, Bundgaard C, Hogg S, Bang AB, Bryan Stensbøl T Journal of pharmacology and experimental therapeutics 2012;340(3):666-675 Citalopram; Vortioxetine 2012 View abstract
Benzodiazepine discontinuation with prolonged-release melatonin: Hints from a German longitudinal prescription database Kunz D, Bineau S, Maman K, Milea D, Toumi M Expert Opinion on Pharmacotherapy 2012;13(1):9-16 - 2012
Characterization of ((3)H)Lu AE60157 (((3)H)8-(4-methylpiperazin-1-yl)-3-phenylsulfonylquinoline) binding to 5-hydroxytryptamine6 (5-HT(6)) receptors in vivo Witten L, Bang-Andersen B, Nielsen SM, Miller S, Christoffersen CT, Stensbol TB, Brennum LT, Arnt J European journal of pharmacology 2012;676:6-11 Sertindole 2012 View abstract
Cardiovascular fitness is associated with altered cortical glucose metabolism during working memory in Epsilon4 carriers Deeny SP, Winchester J, Nichol K, Roth SM, Wu JC, Dick M, Cotman CW Alzheimer's and Dementia 2012. E-published: 8 January 2012 - 2012 View abstract
English title not available Messer T, Schnitker J, Friede M Psychopharmakotherapie 2012;19(1):18-24 Escitalopram 2012 View abstract
Memantine potentiates hippocampal theta oscillations at a therapeutic dose in anesthetized mice: A mechanistic link to its cognitive-enhancing properties Guadagna S, Bundgaard C, Jensen N, Volbracht C, Francis PT, Egebjerg J, Sotty F Neuropharmacology 2012;62(7):2207-2217 Memantine 2012
Indolyl and dihydroindolylN-glycinamides as potent andin vivoactive NPY5 antagonists Wu L, Lu K, Packiarajan M, Jubian V, Chandrasena G, Wolinsky TC, Walker MW Bioorganic and Medicinal Chemistry Letters 2012;22(6):2167-2171 - 2012 View abstract
Physiotherapy exercise after fast-track total hip and knee arthroplasty: time for reconsideration? Bandholm T, Kehlet H Archives of Physical Medicine and Rehabilitation 2012. E-published: 27 February 2012 - 2012
Cost-Effectiveness Evaluation in Sweden of Escitalopram Compared with Venlafaxine Extended-Release as First-Line Treatment in Major Depressive Disorder Nordstrom G, Danchenko N, Despiegel N, Marteau F Value in Health 2012;15(2):231-239 Escitalopram 2012 View abstract
In vitroandin vivoperformance of novel supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS) Thomas N, Holm R, Mullertz A, Rades T Journal of Controlled Release 2012. E-published: 2 March 2012 - 2012
Blockade of the high-affinity norepinephrine transporter (NET) by the selective serotonin reuptake inhibitor escitalopram: an in vivo microdialysis study in mice Nguyen HT, Guiard BP, Bacq A, David DJ, David I, Quesseveur G, Gautron S, Sanchez C, Gardier AM British journal of pharmacology 2012. E-published: Jan 10., 2012 Citalopram 2012
Synergistic antidepressant-like action of gaboxadol and escitalopram Christensen T, Betry C, Mnie-Filali O, Etievant A, Ebert B, Haddjeri N, Wiborg O European neuropsychopharmacology 2012. E-published: Mar 8., 2012 Escitalopram; Gaboxadol 2012
4-(1-Phenyl-1H-pyrazol-4-yl)quinolines as novel, selective and brain penetrant metabotropic glutamate receptor 4 positive allosteric modulators Jimenez HN, Liu KG, Hong SP, Reitman MS, Uberti MA, Bacolod MD, Cajina M, Nattini M, Sabio M, Doller D Bioorganic & Medicinal Chemistry Letters 2012;22(9):3235-3239 - 2012 View abstract
Vascular Occlusion Enables Selecting Acute Ischemic Stroke Patients for Treatment With Desmoteplase Fiebach JB, Al-Rawi Y, Wintermark M, Furlan AJ, Rowley HA, Lindstén A, Smyej J, Eng P, Warach S, Pedraza S Stroke 2012 E-published: Apr 3., 2012 Desmoteplase 2012
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